What are the possible side effects of Anesketin?
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Tell your caregivers at once if you have any of these serious side effects within 24 hours after you receive Anesketin: severe confusion, hallucinations, unusual thoughts, or extreme fear.
Call your doctor at once if you have:
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a light-headed feeling, like you might pass out;
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slow heart rate, weak or shallow breathing;
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pain or burning when you urinate; or
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jerky muscle movements that may look like convulsions.
Common side effects may include:
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dream-like feeling;
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blurred vision, double vision;
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mild dizziness, drowsiness;
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nausea, vomiting, loss of appetite; or
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sleep problems (insomnia).
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Side effects of Anesketin in details
Cardiovascular: Blood pressure and pulse rate are frequently elevated following administration of Anesketin hydrochloride alone. However, hypotension and bradycardia have been observed. Arrhythmia has also occurred.
Respiration: Although respiration is frequently stimulated, severe depression of respiration or apnea may occur following rapid intravenous administration of high doses of Anesketin hydrochloride. Laryngospasms and other forms of airway obstruction have occurred during Anesketin hydrochloride anesthesia.
Eye: Diplopia and nystagmus have been noted following Anesketin hydrochloride administration. It also may cause a slight elevation in intraocular pressure measurement.
Genitourinary: Severe irritative and inflammatory urinary tract and bladder symptoms including cystitis have been reported in individuals with history of chronic Anesketin use or abuse.
Psychological:
Neurological: In some patients, enhanced skeletal muscle tone may be manifested by tonic and clonic movements sometimes resembling seizures.
Gastrointestinal: Anorexia, nausea and vomiting have been observed; however, this is not usually severe and allows the great majority of patients to take liquids by mouth shortly after regaining consciousness.
General: Anaphylaxis. Local pain and exanthema at the injection site have infrequently been reported. Transient erythema and/or morbilliform rash have also been reported.
For medical advice about adverse reactions contact your medical professional. To report SUSPECTED ADVERSE REACTIONS, contact JHP at 1-866-923-2547 or MEDWATCH at 1-800-FDA-1088 (1- 800-332-1088) or http://www.fda.gov/medwatch/.
Drug Abuse And Dependence
Anesketin has been reported being used as a drug of abuse.
Reports suggest that Anesketin produces a variety of symptoms including, but not limited to anxiety, dysphoria, disorientation, insomnia, flashbacks, hallucinations, and psychotic episodes.
Anesketin dependence and tolerance are possible following prolonged administration. A withdrawal syndrome with psychotic features has been described following discontinuation of long-term Anesketin use. Therefore, Anesketin should be prescribed and administered with caution.
What is the most important information I should know about Anesketin?
- Anesketin may cause drowsiness for up to 24 hours. These effects may be worse if you take it with alcohol or certain medicines. Use Anesketin with caution. Do not drive or perform other possibly unsafe tasks for at least 24 hours following surgery until you know how you react to it.
- Anesketin may cause behavior, mental, or mood changes; confusion; or hallucinations that usually go away within 24 hours. Discuss any questions or concerns with your doctor.
- Tell your doctor or dentist that you take Anesketin before you receive any medical or dental care, emergency care, or surgery.
- Use Anesketin with caution in the ELDERLY; they may be more sensitive to its effects.
- Anesketin should be used with extreme caution in CHILDREN younger than 16 years old; safety and effectiveness in these children have not been confirmed.
- PREGNANCY and BREAST-FEEDING: It is not known if Anesketin can cause harm to the fetus. Use of Anesketin during pregnancy is not recommended. If you are or will be breast-feeding while you are using Anesketin, check with your doctor or pharmacist to discuss the risks to your baby.
Anesketin contraindications
You should not receive Anesketin if you are allergic to it, or if you have untreated or uncontrolled hypertension (high blood pressure).
Before you receive Anesketin, tell your doctor if you have heart disease, high blood pressure, a history of alcoholism, or if you recently drank large amounts of alcohol.
Anesketin may be harmful to an unborn baby. Tell your doctor if you are pregnant.
You may feel strange or slightly confused when you first come out of anesthesia. Tell your caregivers if these feelings are severe or unpleasant. It may take you longer to recover from anesthesia with Anesketin if you have recently used a barbiturate (Butisol, Mebaral, Seconal, Nembutal, Solfoton, and others) or narcotic medication (Vicodin, Dilaudid, OxyContin, Percocet, Actiq, Duragesic, Methadose, Dolophine, Kadian, MS Contin, and others).
Tell your caregivers at once if you have any of these serious side effects within 24 hours after you receive Anesketin: severe confusion, hallucinations, unusual thoughts, or extreme fear.
This medication may impair your thinking or reactions. You will probably not be allowed to drive yourself home after your surgery or medical procedure. Avoid driving or operating machinery for at least 24 hours after you have received Anesketin.
Call your doctor at once if you have a serious side effect such as slow heart rate, weak or shallow breathing, feeling like you might pass out, pain or burning when you urinate, or jerky muscle movements that may look like convulsions.
References
- DTP/NCI. "ketamine: The NCI Development Therapeutics Program (DTP) provides services and resources to the academic and private-sector research communities worldwide to facilitate the discovery and development of new cancer therapeutic agents.". https://dtp.cancer.gov/dtpstandard/s... (accessed September 17, 2018).
- European Chemicals Agency - ECHA. "Ketamine: The information provided here is aggregated from the "Notified classification and labelling" from ECHA's C&L Inventory. ". https://echa.europa.eu/information-o... (accessed September 17, 2018).
- HSDB. "KETAMINE". https://toxnet.nlm.nih.gov/cgi-bin/s... (accessed September 17, 2018).
Reviews
The results of a survey conducted on ndrugs.com for Anesketin are given in detail below. The results of the survey conducted are based on the impressions and views of the website users and consumers taking Anesketin. We implore you to kindly base your medical condition or therapeutic choices on the result or test conducted by a physician or licensed medical practitioners.User reports
Consumer reported side effects
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Information checked by Dr. Sachin Kumar, MD Pharmacology
